Researchers' Proposals

We study the molecular epidemiology of the most frequent genetic diseases of

Gypsy populations in Hungary. The genetic structure (including

mitochondrial DNA , Y-chromosome polymorphisms, inbreeding and

pedigre-analyses) of Vlachian, Beasi and Romungro populations of the

Hungarian Gypsy population were analyses by population geneticists. The gene

diagnoses and prenatal diagnoses - if it is possible - of the following

genetic diseases were carried out by molecular biologists.

The following genetic diseases of Gypsy people were studied:

Primer congenital glaucoma, autosom dominant polycystic kidney disease,

herediter haemochromatosis, congenital myasthenic syndrome, epydermolysis

bullosa, medium-chain acyl-CoA dehydrogenase deficiency, biotinidase,

galactocinase deficiency, ceroid lipofusconosis. After the gene diagnoses of

the representative populations Vlachian, Beasi and Romungro Gypsies we would

like to compare the diseases frequencies ( including heterozygote carriers)

of other Gypsy populations living in Europe, Africa and India.